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Deconstructing iNKT cell development at single-cell resolution. Thomas Baranek, Carolina de Amat Herbozo, Thierry Mallevaey, Christophe Paget. Trends Immunol. 2022. doi: 10.1016/

Dirty mice join the immunologist’s toolkit. Kuypers M, Despot T, Mallevaey T. Microb Infec. 2021 Jul; 23(6-7):104817. doi: 10.1016/j.micinf.2021.104817.

Altered Innate-like T Cell Development in Vα14-Jα18 TCRα Transgenic Mice. Lau I, de Amat Herbozo C, Kuypers M, Lin Q, Paget C, Mallevaey T. Immunohorizons. 2020 Dec; 4(12):797-808.

The dialogue between unconventional T cells and the microbiota. Lin Q, Kuypers M, Philpott DJ, Mallevaey T. Mucosal Immunol. 2020 Nov; 13(6):867-876.

High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision. Baranek T, Lebrigand K, de Amat Herbozo C, Gonzalez L, Bogard G, Dietrich C, Magnone V, Boisseau C, Jouan Y, Trottein F, Si-Tahar M, Leite-de-Moraes M, Mallevaey T, Paget C. Cell Rep. 2020 Sep; 32(10):108116. doi:10.1016/j.celrep.2020.108116.


The Protein Phosphatase Shp1 Regulates Invariant NKT Cell Effector Differentiation Independently of TCR and Slam Signaling. Cruz Tleugabulova M, Zhao M, Lau I, Kuypers M, Wirianto C, Umaña JM, Lin Q, Kronenberg M, Mallevaey T. J Immunol. 2019 Apr 15; 202(8):2276-2286.

SLAM receptors foster iNKT cell development by reducing TCR signal strength after positive selection. Lu Y, Zhong MC, Qian J, Calderon V, Cruz Tleugabulova M, Mallevaey T, Veillette A. Nat Immunol. 2019 Apr; 20(4):447-457.

Synthesis of Patient-Specific Nanomaterials. Lazarovits J, Chen YY, Song F, Ngo W, Tavares AJ, Zhang YN, Audet J, Tang B, Lin Q, Tleugabulova MC, Wilhelm S, Krieger JR, Mallevaey T, Chan WCW. Nano Lett. 2019 Jan 9; 19(1):116-123. 

Invariant NKT Cell Activation Is Potentiated by Homotypic trans-Ly108 Interactions. Baglaenko Y, Cruz Tleugabulova M, Gracey E, Talaei N, Manion KP, Chang NH, Ferri DM, Mallevaey T, Wither JE. J Immunol. 2017 May 15; 198(10):3949-3962.

The common mouse protozoa Tritrichomonas muris alters mucosal T cell homeostasis and colitis susceptibility. Escalante NK, Lemire P, Cruz Tleugabulova M, Prescott D, Mortha A, Streutker CJ, Girardin SE, Philpott DJ, Mallevaey T. J Exp Med. 2016 Dec 12; 213(13):2841-2850.

NKT Cell-Deficient Mice Harbor an Altered Microbiota That Fuels Intestinal Inflammation during Chemically Induced Colitis. Selvanantham T, Lin Q, Guo CX, Surendra A, Fieve S, Escalante NK, Guttman DS, Streutker CJ, Robertson SJ, Philpott DJ, Mallevaey TJ Immunol. 2016 Dec 1; 197(11):4464-4472.

Discrete TCR Binding Kinetics Control Invariant NKT Cell Selection and Central Priming. Cruz Tleugabulova M, Escalante NK, Deng S, Fieve S, Ereño-Orbea J, Savage PB, Julien JP, Mallevaey TJ Immunol. 2016 Nov 15; 197(10):3959-3969.

Nod1 and Nod2 enhance TLR-mediated invariant NKT cell activation during bacterial infection. Selvanantham T, Escalante NK, Cruz Tleugabulova M, Fiévé S, Girardin SE, Philpott DJ, Mallevaey TJ Immunol. 2013 Dec 1; 191(11):5646-54.

Strategy of lipid recognition by invariant natural killer T cells: ‘one for all and all for one’. Mallevaey T, Selvanantham T. Immunology. 2012 Jul; 136(3):273-82.

A molecular basis for NKT cell recognition of CD1d-self-antigen. Mallevaey T, Clarke AJ, Scott-Browne JP, Young MH, Roisman LC, Pellicci DG, Patel O, Vivian JP, Matsuda JL, McCluskey J, Godfrey DI, Marrack P, Rossjohn J, Gapin L. Immunity. 2011 Mar 25; 34(3):315-26.


T cell receptor CDR2 beta and CDR3 beta loops collaborate functionally to shape the iNKT cell repertoire. Mallevaey T, Scott-Browne JP, Matsuda JL, Young MH, Pellicci DG, Patel O, Thakur M, Kjer-Nielsen L, Richardson SK, Cerundolo V, Howell AR, McCluskey J, Godfrey DI, Rossjohn J, Marrack P, Gapin L. Immunity. 2009 Jul 17; 31(1):60-71.